| has gloss | eng: The Streptamer technology allows the reversible isolation and staining of antigen-specific T-cells. This technology combines a current T-cell isolation method with the Strep-tag technology. In princible, the T-cells are separated by establishing a specific interaction between the T-cell of interest and a molecule that is conjugated to a marker, which enables the isolation. The reversibility of this interaction and the fact that it can be performed at low temperatures is the reason for the successful isolation and characterization of functional T-cells. Because T-cells remain phenotypically and functionally indistinguishable from untreated cells, this method may offer new strategies in clinical and basic T-cell research. |
